Edward C. Keystone

Edward C. Keystone, MD, FRCP(C)


Professor Emeritus, Department of Medicine, University of Toronto
Honorary Staff, Sinai Health System

Medical/Professional Training:
Dr. Keystone obtained his Doctorate of Medicine degree from the University of Toronto in 1969. After a further five years of training in Rheumatology, he received his specialty degrees (or fellowships) in both Rheumatology and Internal Medicine in 1974. He then carried out his research training at the Clinical Research Centre in Harrow, London, UK until 1976. He was on staff as a consultant rheumatologist at The Wellesley Central Hospital, Toronto, Canada from 1976 to 1998.

Professional and Academic Activities:
Dr. Keystone became an Emeritus Professor in the Department of Medicine at the University of Toronto as of January 2021. He was a Senior Consultant in Rheumatology at Mount Sinai Hospital from 1998 to 2020. He currently holds an Honorary Staff position at Mount Sinai Hospital as of 2021.

In 2003 Dr. Keystone established The Rebecca Macdonald Centre for Arthritis and Autoimmune Disease – a centre devoted to research in genomics, therapeutics, and outcomes in autoimmune inflammatory joint disease. He was Director of the Centre and headed the Advanced Therapeutics Division which focused on novel therapeutics in Rheumatoid Arthritis until 2019. Dr. Keystone is a consultant to the pharmaceutical and biotechnology industry, and is a member of numerous national and international biopharmaceutical advisory boards.

Research and Teaching:
Dr. Keystone is also involved in research related to therapeutic outcomes in clinical trials and surveillance databases as well as translational research studies in Rheumatoid Arthritis. He is the author of over 300 peer-reviewed papers and more than 100 book chapters, reviews and invited papers. He has been the recipient of numerous honours, including the Senior Investigator Award of the Canadian Rheumatology Association and the prestigious American College of Rheumatology’s lifetime Grand Master Award in 2008. Dr. Keystone also received a Lifetime Excellence in Rheumatology Teaching Award at the Rheumatology Winter Clinical Symposium Conference in January 2011 well as the Congress of Clinical Rheumatology Outstanding Speaker Award in the spring of 2011. In 2012, Dr. Keystone was chosen an “Alumni of Influence” by the University College of The University of Toronto, Canada. In 2014 he was awarded “Rheumatologist of the Year, by the Ontario Rheumatology Association. In 2019, Dr. Keystone received the Distinguished Rheumatologist Award from The Canadian Rheumatology Association (CRA). In February 2020, Dr. Keystone was one of the first rheumatologists in Canada to receive the inaugural CRA Master Rheumatologist Award.

Dr. Keystone is married with a son and two daughters, and two delightful grandchildren!